Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells

Our understanding of cell fate decisions in hematopoietic stem cells is incomplete. Here, we show that the transcription factor Helios is highly expressed in murine hematopoietic stem and progenitor cells (HSPCs), where it is required to suppress the separation of the platelet/megakaryocyte lineage...

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Detalles Bibliográficos
Autores principales: Cova, Giovanni, Taroni, Chiara, Deau, Marie-Céline, Cai, Qi, Mittelheisser, Vincent, Philipps, Muriel, Jung, Matthieu, Cerciat, Marie, Le Gras, Stéphanie, Thibault-Carpentier, Christelle, Jost, Bernard, Carlsson, Leif, Thornton, Angela M., Shevach, Ethan M., Kirstetter, Peggy, Kastner, Philippe, Chan, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406645/
https://www.ncbi.nlm.nih.gov/pubmed/34459852
http://dx.doi.org/10.1084/jem.20202317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406645/
https://www.ncbi.nlm.nih.gov/pubmed/34459852
http://dx.doi.org/10.1084/jem.20202317

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