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Rapamycin suppresses the PI3K/AKT/mTOR signaling pathway by targeting SIRT1 in esophageal cancer

Rapamycin, a secondary metabolite produced by Streptomyces hygroscopicus, is known for its pharmacological effects, especially antitumor and immunosuppressive activities. However, the antitumoral effects of rapamycin in human esophageal cancer (EC) are still poorly understood. To investigate the pot...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Liang, Xiangsen, Sun, Yu, Yang, Shengzhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406672/
https://www.ncbi.nlm.nih.gov/pubmed/34475980
http://dx.doi.org/10.3892/etm.2021.10624