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Ikzf2 Regulates the Development of ICOS(+) Th Cells to Mediate Immune Response in the Spleen of S. japonicum-Infected C57BL/6 Mice

BACKGROUND: Th cells (helper T cells) have multiple functions in Schistosoma japonicum (S. japonicum) infection. Inducible co-stimulator (ICOS) is induced and expressed in activated T lymphocytes, which enhances the development of B cells and antibody production through the ICOS/ICOSL pathway. It re...

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Detalles Bibliográficos
Autores principales: Xie, Shihao, Wei, Haixia, Peng, Anping, Xie, Anqi, Li, Jiajie, Fang, Chao, Shi, Feihu, Yang, Quan, Huang, He, Xie, Hongyan, Pan, Xingfei, Tian, Xu, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406689/
https://www.ncbi.nlm.nih.gov/pubmed/34475870
http://dx.doi.org/10.3389/fimmu.2021.687919