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PTK7-Targeting CAR T-Cells for the Treatment of Lung Cancer and Other Malignancies

In spite of impressive success in treating hematologic malignancies, adoptive therapy with chimeric antigen receptor modified T cells (CAR T) has not yet been effective in solid tumors, where identification of suitable tumor-specific antigens remains a major obstacle for CAR T-cell therapy due to th...

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Detalles Bibliográficos
Autores principales: Jie, Yamin, Liu, Guijun, Feng, Lina, Li, Ying, E, Mingyan, Wu, Liangliang, Li, Yinyin, Rong, Guanghua, Li, Yongwu, Wei, Huafeng, Gu, Anxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406764/
https://www.ncbi.nlm.nih.gov/pubmed/34475869
http://dx.doi.org/10.3389/fimmu.2021.665970