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PTK7-Targeting CAR T-Cells for the Treatment of Lung Cancer and Other Malignancies
In spite of impressive success in treating hematologic malignancies, adoptive therapy with chimeric antigen receptor modified T cells (CAR T) has not yet been effective in solid tumors, where identification of suitable tumor-specific antigens remains a major obstacle for CAR T-cell therapy due to th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406764/ https://www.ncbi.nlm.nih.gov/pubmed/34475869 http://dx.doi.org/10.3389/fimmu.2021.665970 |