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Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells

Reactive astrogliosis is a key hallmark of inflammatory responses in the pathogenesis of brain injury, including Parkinson’s disease (PD), but its role and regulatory mechanisms are not fully understood. Pannexin 1 (Panx 1) is a membrane channel that mediates substance release in many neurodegenerat...

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Detalles Bibliográficos
Autores principales: Ling, Zhuo-Min, Wang, Qian, Ma, Yu, Xue, Peng, Gu, Yun, Cao, Mao-Hong, Wei, Zhong-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406772/
https://www.ncbi.nlm.nih.gov/pubmed/34475813
http://dx.doi.org/10.3389/fncel.2021.710820