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Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis

Angiogenesis and vasculogenic mimicry (VM) are considered to be the main processes to ensure tumor blood supply during the proliferation and metastasis of choroidal melanoma (CM). The traditional antimalarial drug artesunate (ART) has some potential anti-CM effects; however, the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Geng, Bochao, Zhu, Yuanzhang, Yuan, Yingying, Bai, Jingyi, Dou, Zhizhi, Sui, Aihua, Luo, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406848/
https://www.ncbi.nlm.nih.gov/pubmed/34476217
http://dx.doi.org/10.3389/fonc.2021.714646