Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival

T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts. These qualities and the lack of an effective treatment for the chronic stage of the disease have contributed to the durability...

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Detalles Bibliográficos
Autores principales: Rivero, Cynthia Vanesa, Martínez, Santiago José, Novick, Paul, Cueto, Juan Agustín, Salassa, Betiana Nebaí, Vanrell, María Cristina, Li, Xiaomo, Labriola, Carlos Alberto, Polo, Luis Mariano, Engman, David M., Clos, Joachim, Romano, Patricia Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406938/
https://www.ncbi.nlm.nih.gov/pubmed/34476220
http://dx.doi.org/10.3389/fcimb.2021.657257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406938/
https://www.ncbi.nlm.nih.gov/pubmed/34476220
http://dx.doi.org/10.3389/fcimb.2021.657257

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