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Functional microRNA targetome undergoes degeneration-induced shift in the retina

BACKGROUND: MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with argonaute 2 (AGO2) - a key member of the RNA Induced Silenci...

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Detalles Bibliográficos
Autores principales:	Chu-Tan, Joshua A., Cioanca, Adrian V., Feng, Zhi-Ping, Wooff, Yvette, Schumann, Ulrike, Aggio-Bruce, Riemke, Patel, Hardip, Rutar, Matt, Hannan, Katherine, Panov, Konstantin, Provis, Jan, Natoli, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406976/ https://www.ncbi.nlm.nih.gov/pubmed/34465369 http://dx.doi.org/10.1186/s13024-021-00478-9

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