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An Integrative Approach to Determine 3D Protein Structures Using Sparse Paramagnetic NMR Data and Physical Modeling

Paramagnetic nuclear magnetic resonance (NMR) methods have emerged as powerful tools for structure determination of large, sparsely protonated proteins. However traditional applications face several challenges, including a need for large datasets to offset the sparsity of restraints, the difficulty...

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Detalles Bibliográficos
Autores principales: Gaalswyk, Kari, Liu, Zhihong, Vogel, Hans J., MacCallum, Justin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407082/
https://www.ncbi.nlm.nih.gov/pubmed/34476238
http://dx.doi.org/10.3389/fmolb.2021.676268