Hypoxia-inducible transcription factor-1α inhibition by topotecan protects against lipopolysaccharide-induced inflammation and apoptosis of cardiomyocytes

BACKGROUND: Myocarditis, an inflammatory disease of the myocardium, is a serious hazard to human life due to the expansion of inflammatory lesions in the myocardium. The aim of this study was to investigate the role of hypoxia-inducible transcription factor (HIF)-1α and its inhibitor topotecan in th...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Xu, Yi, Zhou, Ke, Kao, Guoying, Yan, Meng, Xiao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407092/
https://www.ncbi.nlm.nih.gov/pubmed/34465337
http://dx.doi.org/10.1186/s12938-021-00923-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407092/
https://www.ncbi.nlm.nih.gov/pubmed/34465337
http://dx.doi.org/10.1186/s12938-021-00923-2

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