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Hypoxia-inducible transcription factor-1α inhibition by topotecan protects against lipopolysaccharide-induced inflammation and apoptosis of cardiomyocytes

BACKGROUND: Myocarditis, an inflammatory disease of the myocardium, is a serious hazard to human life due to the expansion of inflammatory lesions in the myocardium. The aim of this study was to investigate the role of hypoxia-inducible transcription factor (HIF)-1α and its inhibitor topotecan in th...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Xu, Yi, Zhou, Ke, Kao, Guoying, Yan, Meng, Xiao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407092/ https://www.ncbi.nlm.nih.gov/pubmed/34465337 http://dx.doi.org/10.1186/s12938-021-00923-2

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