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Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase

BACKGROUND AND PURPOSE: Alzheimer’s disease is considered one of the lead causes of elderly death around the world. A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer’s disease, therefore acetylcholinesterase (AChE) inhibitors such as donepezil and r...

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Detalles Bibliográficos
Autores principales: Hassanzadeh, Motahareh, Hassanzadeh, Farshid, khodarahmi, Ghadam Ali, Rostami, Mahbobe, Azimi, Fateme, Nadri, Hamid, Homayouni Moghadam, Farshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407153/
https://www.ncbi.nlm.nih.gov/pubmed/34522196
http://dx.doi.org/10.4103/1735-5362.323915