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Assessing tumor heterogeneity: integrating tissue and circulating tumor DNA (ctDNA) analysis in the era of immuno-oncology - blood TMB is not the same as tissue TMB

Tissue tumor mutational burden (tTMB) is calculated to aid in cancer treatment selection. High tTMB predicts a favorable response to immunotherapy in patients with non-small cell lung cancer. Blood TMB (bTMB) from circulating tumor DNA is reported to have similar predictive power and has been propos...

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Detalles Bibliográficos
Autores principales:	Fridland, Stanislav, Choi, Jaeyoun, Nam, Myungwoo, Schellenberg, Samuel Joseph, Kim, Eugene, Lee, Grace, Yoon, Nathaniel, Chae, Young Kwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407207/ https://www.ncbi.nlm.nih.gov/pubmed/34462324 http://dx.doi.org/10.1136/jitc-2021-002551

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