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CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell
BACKGROUND: Increasing infiltration of CD8(+) T cells within tumor tissue predicts a better prognosis and is essential for response to checkpoint blocking therapy. Furthermore, current clinical protocols use unfractioned T cell populations as the starting point for transduction of chimeric antigen r...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407215/ https://www.ncbi.nlm.nih.gov/pubmed/34462326 http://dx.doi.org/10.1136/jitc-2021-003100 |