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CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell

BACKGROUND: Increasing infiltration of CD8(+) T cells within tumor tissue predicts a better prognosis and is essential for response to checkpoint blocking therapy. Furthermore, current clinical protocols use unfractioned T cell populations as the starting point for transduction of chimeric antigen r...

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Detalles Bibliográficos
Autores principales: Wang, Binglin, Wang, Yi, Sun, Xiaofan, Deng, Guoliang, Huang, Wei, Wu, Xingxin, Gu, Yanghong, Tian, Zhigang, Fan, Zhimin, Xu, Qiang, Chen, Hongqi, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407215/
https://www.ncbi.nlm.nih.gov/pubmed/34462326
http://dx.doi.org/10.1136/jitc-2021-003100