A CRISPR Interference Screen of Essential Genes Reveals that Proteasome Regulation Dictates Acetic Acid Tolerance in Saccharomyces cerevisiae

CRISPR interference (CRISPRi) is a powerful tool to study cellular physiology under different growth conditions, and this technology provides a means for screening changed expression of essential genes. In this study, a Saccharomyces cerevisiae CRISPRi library was screened for growth in medium suppl...

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Detalles Bibliográficos
Autores principales: Mukherjee, Vaskar, Lind, Ulrika, St. Onge, Robert P., Blomberg, Anders, Nygård, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407339/
https://www.ncbi.nlm.nih.gov/pubmed/34313457
http://dx.doi.org/10.1128/mSystems.00418-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407339/
https://www.ncbi.nlm.nih.gov/pubmed/34313457
http://dx.doi.org/10.1128/mSystems.00418-21

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