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Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

Treponema pallidum, an obligate human pathogen, has an outer membrane (OM) whose physical properties, ultrastructure, and composition differ markedly from those of phylogenetically distant Gram-negative bacteria. We developed structural models for the outer membrane protein (OMP) repertoire (OMPeome...

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Detalles Bibliográficos
Autores principales: Hawley, Kelly L., Montezuma-Rusca, Jairo M., Delgado, Kristina N., Singh, Navreeta, Uversky, Vladimir N., Caimano, Melissa J., Radolf, Justin D., Luthra, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407342/
https://www.ncbi.nlm.nih.gov/pubmed/33972353
http://dx.doi.org/10.1128/JB.00082-21