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Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine
Treponema pallidum, an obligate human pathogen, has an outer membrane (OM) whose physical properties, ultrastructure, and composition differ markedly from those of phylogenetically distant Gram-negative bacteria. We developed structural models for the outer membrane protein (OMP) repertoire (OMPeome...
Autores principales: | Hawley, Kelly L., Montezuma-Rusca, Jairo M., Delgado, Kristina N., Singh, Navreeta, Uversky, Vladimir N., Caimano, Melissa J., Radolf, Justin D., Luthra, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407342/ https://www.ncbi.nlm.nih.gov/pubmed/33972353 http://dx.doi.org/10.1128/JB.00082-21 |
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