Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study

BACKGROUND: The leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of NF1, this cancer type frequently arises from with...

Descripción completa

Detalles Bibliográficos
Autores principales: Szymanski, Jeffrey J., Sundby, R. Taylor, Jones, Paul A., Srihari, Divya, Earland, Noah, Harris, Peter K., Feng, Wenjia, Qaium, Faridi, Lei, Haiyan, Roberts, David, Landeau, Michele, Bell, Jamie, Huang, Yi, Hoffman, Leah, Spencer, Melissa, Spraker, Matthew B., Ding, Li, Widemann, Brigitte C., Shern, Jack F., Hirbe, Angela C., Chaudhuri, Aadel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407545/
https://www.ncbi.nlm.nih.gov/pubmed/34464388
http://dx.doi.org/10.1371/journal.pmed.1003734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407545/
https://www.ncbi.nlm.nih.gov/pubmed/34464388
http://dx.doi.org/10.1371/journal.pmed.1003734

Ejemplares similares