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Bone marrow-derived mesenchymal stem cells transplanted into a vascularized biodegradable tube containing decellularized allogenic nerve basal laminae promoted peripheral nerve regeneration; can it be an alternative of autologous nerve graft?

Previously, we showed silicone nerve conduits containing a vascular bundle and decellularized allogenic basal laminae (DABLs) seeded with bone marrow-derived mesenchymal stem cells (BMSCs) demonstrated successful nerve regeneration. Nerve conduits should be flexible and biodegradable for clinical us...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Kakinoki, Ryosuke, Kaizawa, Yukitoshi, Yurie, Hirofumi, Ikeguchi, Ryosuke, Akagi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407554/
https://www.ncbi.nlm.nih.gov/pubmed/34464381
http://dx.doi.org/10.1371/journal.pone.0254968