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Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies

PURPOSE: In pancreatic cancer (PC), the RAF family alterations define a rare subset of patients that may predict response to inhibition of the BRAF/MEK/ERK signaling pathway. A comprehensive understanding of the molecular and clinical characteristics of RAF-mutated PC may support future development...

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Detalles Bibliográficos
Autores principales: Hendifar, Andrew, Blais, Edik M., Wolpin, Brian, Subbiah, Vivek, Collisson, Eric, Singh, Isha, Cannon, Timothy, Shaw, Kenna, Petricoin, Emanuel F., Klempner, Samuel, Lyons, Emily, Wang-Gillam, Andrea, Pishvaian, Michael J., O'Reilly, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407652/
https://www.ncbi.nlm.nih.gov/pubmed/34476331
http://dx.doi.org/10.1200/PO.20.00494