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Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies
PURPOSE: In pancreatic cancer (PC), the RAF family alterations define a rare subset of patients that may predict response to inhibition of the BRAF/MEK/ERK signaling pathway. A comprehensive understanding of the molecular and clinical characteristics of RAF-mutated PC may support future development...
Autores principales: | Hendifar, Andrew, Blais, Edik M., Wolpin, Brian, Subbiah, Vivek, Collisson, Eric, Singh, Isha, Cannon, Timothy, Shaw, Kenna, Petricoin, Emanuel F., Klempner, Samuel, Lyons, Emily, Wang-Gillam, Andrea, Pishvaian, Michael J., O'Reilly, Eileen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407652/ https://www.ncbi.nlm.nih.gov/pubmed/34476331 http://dx.doi.org/10.1200/PO.20.00494 |
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