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The use of negative control outcomes in Mendelian randomization to detect potential population stratification
A key assumption of Mendelian randomization (MR) analysis is that there is no association between the genetic variants used as instruments and the outcome other than through the exposure of interest. One way in which this assumption can be violated is through population stratification, which can int...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407870/ https://www.ncbi.nlm.nih.gov/pubmed/33570130 http://dx.doi.org/10.1093/ije/dyaa288 |