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Cornel Iridoid Glycoside Ameliorated Alzheimer's Disease-Like Pathologies and Necroptosis through RIPK1/MLKL Pathway in Young and Aged SAMP8 Mice

BACKGROUND: Aging is an important risk factor for sporadic Alzheimer's disease (AD) and other neurodegenerative diseases. Senescence-accelerated mouse-prone 8 (SAMP8) is used as an animal model for brain aging and sporadic AD research studies. The aim of the current study was to investigate the...

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Detalles Bibliográficos
Autores principales: Ma, Denglei, Li, Yanzheng, Zhu, Yanqiu, Wei, Weipeng, Zhang, Li, Li, Yali, Li, Lin, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407981/
https://www.ncbi.nlm.nih.gov/pubmed/34475966
http://dx.doi.org/10.1155/2021/9920962