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The miR-193a-5p/NCX2/AKT axis promotes invasion and metastasis of osteosarcoma

MiR-193a-5p has been observed to have oncogenic or tumor suppressive functions in different kinds of cancers, but its role and molecular mechanism in osteosarcoma are elusive. Na(+)/Ca(2+) exchangers (NCX1, NCX2 and NCX3) normally extrude Ca(2+) from the cell, and deregulation of the intracellular C...

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Detalles Bibliográficos
Autores principales: Chen, Ruiqi, Ning, Yichong, Zeng, Guirong, Zhou, Hao, Zhou, Lin, Xiao, Pei, Li, Zhihong, Zhou, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408106/
https://www.ncbi.nlm.nih.gov/pubmed/34476004
http://dx.doi.org/10.7150/jca.60969