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Phytosterol accumulation results in ventricular arrhythmia, impaired cardiac function and death in mice

Heart failure (HF) and cardiac arrhythmias share overlapping pathological mechanisms that act cooperatively to accelerate disease pathogenesis. Cardiac fibrosis is associated with both pathological conditions. Our previous work identified a link between phytosterol accumulation and cardiac injury in...

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Detalles Bibliográficos
Autores principales: Ge, Hongfei, Liu, Gongxin, Yamawaki, Tracy M., Tao, Caroline, Alexander, Shawn T., Ly, Kimberly, Fordstrom, Preston, Shkumatov, Artem A., Li, Chi-Ming, Rajamani, Sridharan, Zhou, Mingyue, Ason, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408133/
https://www.ncbi.nlm.nih.gov/pubmed/34465831
http://dx.doi.org/10.1038/s41598-021-96936-x