Osteoblastic glucocorticoid signaling exacerbates high-fat-diet- induced bone loss and obesity

Chronic high-fat diet (HFD) consumption not only promotes obesity and insulin resistance, but also causes bone loss through mechanisms that are not well understood. Here, we fed wild-type CD-1 mice either chow or a HFD (43% of energy from fat) for 18 weeks; HFD-fed mice exhibited decreased trabecula...

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Detalles Bibliográficos
Autores principales: Kim, Sarah, Henneicke, Holger, Cavanagh, Lauryn L., Macfarlane, Eugenie, Thai, Lee Joanne, Foong, Daphne, Gasparini, Sylvia J., Fong-Yee, Colette, Swarbrick, Michael M., Seibel, Markus J., Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408138/
https://www.ncbi.nlm.nih.gov/pubmed/34465731
http://dx.doi.org/10.1038/s41413-021-00159-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408138/
https://www.ncbi.nlm.nih.gov/pubmed/34465731
http://dx.doi.org/10.1038/s41413-021-00159-9

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