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The RhoA dependent anti-metastatic function of RKIP in breast cancer

Raf-1 kinase inhibitor protein was initially discovered as a physiological kinase inhibitor of the MAPK signaling pathway and was later shown to suppress cancer cell invasion and metastasis. Yet, the molecular mechanism through which RKIP executes its effects is not completely defined. RhoA has both...

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Detalles Bibliográficos
Autores principales: Kalpana, Gardiyawasam, Figy, Christopher, Feng, Jingwei, Tipton, Claire, De Castro, Julius N., Bach, Vu N., Borile, Clariza, LaSalla, Alexandria, Odeh, Hussain N., Yeung, Miranda, Garcia-Mata, Rafael, Yeung, Kam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408146/
https://www.ncbi.nlm.nih.gov/pubmed/34465801
http://dx.doi.org/10.1038/s41598-021-96709-6