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The RhoA dependent anti-metastatic function of RKIP in breast cancer
Raf-1 kinase inhibitor protein was initially discovered as a physiological kinase inhibitor of the MAPK signaling pathway and was later shown to suppress cancer cell invasion and metastasis. Yet, the molecular mechanism through which RKIP executes its effects is not completely defined. RhoA has both...
Autores principales: | Kalpana, Gardiyawasam, Figy, Christopher, Feng, Jingwei, Tipton, Claire, De Castro, Julius N., Bach, Vu N., Borile, Clariza, LaSalla, Alexandria, Odeh, Hussain N., Yeung, Miranda, Garcia-Mata, Rafael, Yeung, Kam C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408146/ https://www.ncbi.nlm.nih.gov/pubmed/34465801 http://dx.doi.org/10.1038/s41598-021-96709-6 |
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