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Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma

Plasmablastic lymphoma (PBL) represents a rare and aggressive lymphoma subtype frequently associated with immunosuppression. Clinically, patients with PBL are characterized by poor outcome. The current understanding of the molecular pathogenesis is limited. A hallmark of PBL represents its plasmacyt...

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Detalles Bibliográficos
Autores principales: Frontzek, Fabian, Staiger, Annette M., Zapukhlyak, Myroslav, Xu, Wendan, Bonzheim, Irina, Borgmann, Vanessa, Sander, Philip, Baptista, Maria Joao, Heming, Jan-Niklas, Berning, Philipp, Wullenkord, Ramona, Erdmann, Tabea, Lutz, Mathias, Veratti, Pia, Ehrenfeld, Sophia, Wienand, Kirsty, Horn, Heike, Goodlad, John R., Wilson, Matthew R., Anagnostopoulos, Ioannis, Lamping, Mario, Gonzalez-Barca, Eva, Climent, Fina, Salar, Antonio, Castellvi, Josep, Abrisqueta, Pau, Menarguez, Javier, Aldamiz, Teresa, Richter, Julia, Klapper, Wolfram, Tzankov, Alexandar, Dirnhofer, Stefan, Rosenwald, Andreas, Mate, José Luis, Tapia, Gustavo, Lenz, Peter, Miething, Cornelius, Hartmann, Wolfgang, Chapuy, Björn, Fend, Falko, Ott, German, Navarro, José-Tomas, Grau, Michael, Lenz, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408158/
https://www.ncbi.nlm.nih.gov/pubmed/34465776
http://dx.doi.org/10.1038/s41467-021-25405-w