Changes in the distribution of fitness effects and adaptive mutational spectra following a single first step towards adaptation

Historical contingency and diminishing returns epistasis have been typically studied for relatively divergent genotypes and/or over long evolutionary timescales. Here, we use Saccharomyces cerevisiae to study the extent of diminishing returns and the changes in the adaptive mutational spectra follow...

Descripción completa

Detalles Bibliográficos
Autores principales: Aggeli, Dimitra, Li, Yuping, Sherlock, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408183/
https://www.ncbi.nlm.nih.gov/pubmed/34465770
http://dx.doi.org/10.1038/s41467-021-25440-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408183/
https://www.ncbi.nlm.nih.gov/pubmed/34465770
http://dx.doi.org/10.1038/s41467-021-25440-7

Ejemplares similares