The phosphodiesterase 4 inhibitor AA6216 suppresses activity of fibrosis-specific macrophages

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, with a poor prognosis. We previously showed the antifibrotic effects of a novel phosphodiesterase 4 (PDE4) inhibitor, AA6216. In this study, we examined the effect of...

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Detalles Bibliográficos
Autores principales: Matsuhira, Takashi, Nishiyama, Osamu, Tabata, Yuji, Kurashimo, Shinji, Sano, Hiroyuki, Iwanaga, Takashi, Tohda, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408426/
https://www.ncbi.nlm.nih.gov/pubmed/34485715
http://dx.doi.org/10.1016/j.bbrep.2021.101118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408426/
https://www.ncbi.nlm.nih.gov/pubmed/34485715
http://dx.doi.org/10.1016/j.bbrep.2021.101118

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