Diagnostic Value of the CSF α-Synuclein Real-Time Quaking-Induced Conversion Assay at the Prodromal MCI Stage of Dementia With Lewy Bodies

OBJECTIVE: To investigate whether the CSF α-synuclein (α-syn) real-time quaking-induced conversion (RT-QuIC) assay accurately identifies patients with mild cognitive impairment (MCI) due to probable Lewy body (LB) disease. METHODS: We applied α-syn RT-QuIC to 289 CSF samples obtained from 2 independ...

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Detalles Bibliográficos
Autores principales: Rossi, Marcello, Baiardi, Simone, Teunissen, Charlotte E., Quadalti, Corinne, van de Beek, Marleen, Mammana, Angela, Stanzani-Maserati, Michelangelo, Van der Flier, Wiesje M., Sambati, Luisa, Zenesini, Corrado, Caughey, Byron, Capellari, Sabina, Lemstra, Afina W., Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408510/
https://www.ncbi.nlm.nih.gov/pubmed/34210822
http://dx.doi.org/10.1212/WNL.0000000000012438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408510/
https://www.ncbi.nlm.nih.gov/pubmed/34210822
http://dx.doi.org/10.1212/WNL.0000000000012438

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