Cardiotoxicity assessment using 3D vascularized cardiac tissue consisting of human iPSC-derived cardiomyocytes and fibroblasts

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for cardiac safety assessment but have limitations for the evaluation of drug-induced contractility. Three-dimensional (3D) cardiac tissues are similar to native tissue and valuable for the assessment of contractility. H...

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Detalles Bibliográficos
Autores principales: Tadano, Kiyoshi, Miyagawa, Shigeru, Takeda, Maki, Tsukamoto, Yoshinari, Kazusa, Katsuyuki, Takamatsu, Kazuhiko, Akashi, Mitsuru, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408525/
https://www.ncbi.nlm.nih.gov/pubmed/34514026
http://dx.doi.org/10.1016/j.omtm.2021.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408525/
https://www.ncbi.nlm.nih.gov/pubmed/34514026
http://dx.doi.org/10.1016/j.omtm.2021.05.007

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