Cargando…

Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin

Recombinant antibodies with well-characterized epitopes and known conformational specificities are critical reagents to support robust interpretation and reproducibility of immunoassays across biomedical research. For myocilin, a protein prone to misfolding that is associated with glaucoma and an em...

Descripción completa

Detalles Bibliográficos
Autores principales: Patterson-Orazem, Athéna C., Qerqez, Ahlam N., Azouz, Laura R., Ma, Minh Thu, Hill, Shannon E., Ku, Yemo, Schildmeyer, Lisa A., Maynard, Jennifer A., Lieberman, Raquel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408531/
https://www.ncbi.nlm.nih.gov/pubmed/34384785
http://dx.doi.org/10.1016/j.jbc.2021.101067