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Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin
Recombinant antibodies with well-characterized epitopes and known conformational specificities are critical reagents to support robust interpretation and reproducibility of immunoassays across biomedical research. For myocilin, a protein prone to misfolding that is associated with glaucoma and an em...
Autores principales: | Patterson-Orazem, Athéna C., Qerqez, Ahlam N., Azouz, Laura R., Ma, Minh Thu, Hill, Shannon E., Ku, Yemo, Schildmeyer, Lisa A., Maynard, Jennifer A., Lieberman, Raquel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408531/ https://www.ncbi.nlm.nih.gov/pubmed/34384785 http://dx.doi.org/10.1016/j.jbc.2021.101067 |
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