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Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects

Breast cancer (BC) is the most common malignancy in women. Particular subtypes with aggressive behavior are major contributors to poor outcomes. Triple-negative breast cancer (TNBC) is difficult to treat, pro-inflammatory, and highly metastatic. We demonstrate that TNBC cells express TLR9 and are re...

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Detalles Bibliográficos
Autores principales: Eteshola, Elias O.U., Landa, Karenia, Rempel, Rachel E., Naqvi, Ibtehaj A., Hwang, E. Shelley, Nair, Smita K., Sullenger, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408553/
https://www.ncbi.nlm.nih.gov/pubmed/34513289
http://dx.doi.org/10.1016/j.omtn.2021.06.016