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FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway

N6-methyladenosine (m(6)A) modification plays a critical role in mammalian development. However, the role of m(6)A in the skeletal muscle development remains largely unknown. Here, we report a global m(6)A modification pattern of goat skeletal muscle at two key development stages and identified that...

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Detalles Bibliográficos
Autores principales: Deng, Kaiping, Fan, Yixuan, Liang, Yaxu, Cai, Yu, Zhang, Guomin, Deng, Mingtian, Wang, Zhibo, Lu, Jiawei, Shi, Jianfei, Wang, Feng, Zhang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408560/
https://www.ncbi.nlm.nih.gov/pubmed/34513292
http://dx.doi.org/10.1016/j.omtn.2021.06.013