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Torsin and NEP1R1‐CTDNEP1 phosphatase affect interphase nuclear pore complex insertion by lipid‐dependent and lipid‐independent mechanisms

The interphase nuclear envelope (NE) is extensively remodeled during nuclear pore complex (NPC) insertion. How this remodeling occurs and why it requires Torsin ATPases, which also regulate lipid metabolism, remains poorly understood. Here, we show that Drosophila Torsin (dTorsin) affects lipid meta...

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Detalles Bibliográficos
Autores principales: Jacquemyn, Julie, Foroozandeh, Joyce, Vints, Katlijn, Swerts, Jef, Verstreken, Patrik, Gounko, Natalia V, Gallego, Sandra F, Goodchild, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408595/
https://www.ncbi.nlm.nih.gov/pubmed/34313336
http://dx.doi.org/10.15252/embj.2020106914