A CRMP4‐dependent retrograde axon‐to‐soma death signal in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal non‐cell‐autonomous neurodegenerative disease characterized by the loss of motor neurons (MNs). Mutations in CRMP4 are associated with ALS in patients, and elevated levels of CRMP4 are suggested to affect MN health in the SOD1(G93A)‐ALS mouse model. How...

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Detalles Bibliográficos
Autores principales: Maimon, Roy, Ankol, Lior, Gradus Pery, Tal, Altman, Topaz, Ionescu, Ariel, Weissova, Romana, Ostrovsky, Michael, Tank, Elizabeth, Alexandra, Gayster, Shelestovich, Natalia, Opatowsky, Yarden, Dori, Amir, Barmada, Sami, Balastik, Martin, Perlson, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408612/
https://www.ncbi.nlm.nih.gov/pubmed/34190355
http://dx.doi.org/10.15252/embj.2020107586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408612/
https://www.ncbi.nlm.nih.gov/pubmed/34190355
http://dx.doi.org/10.15252/embj.2020107586

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