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Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension

Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the pathogenesis of chronic kidney disease (CKD), diabetes, obesity and atherosclerosis. We test, whether TMAO augments angiotensin II (Ang II)-in...

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Detalles Bibliográficos
Autores principales: Jiang, Shan, Shui, Yongjie, Cui, Yu, Tang, Chun, Wang, Xiaohua, Qiu, Xingyu, Hu, Weipeng, Fei, Lingyan, Li, Yun, Zhang, Suping, Zhao, Liang, Xu, Nan, Dong, Fang, Ren, Xiaoqiu, Liu, Ruisheng, Persson, Pontus B., Patzak, Andreas, Lai, En Yin, Wei, Qichun, Zheng, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408632/
https://www.ncbi.nlm.nih.gov/pubmed/34474396
http://dx.doi.org/10.1016/j.redox.2021.102115