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Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension
Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the pathogenesis of chronic kidney disease (CKD), diabetes, obesity and atherosclerosis. We test, whether TMAO augments angiotensin II (Ang II)-in...
Autores principales: | Jiang, Shan, Shui, Yongjie, Cui, Yu, Tang, Chun, Wang, Xiaohua, Qiu, Xingyu, Hu, Weipeng, Fei, Lingyan, Li, Yun, Zhang, Suping, Zhao, Liang, Xu, Nan, Dong, Fang, Ren, Xiaoqiu, Liu, Ruisheng, Persson, Pontus B., Patzak, Andreas, Lai, En Yin, Wei, Qichun, Zheng, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408632/ https://www.ncbi.nlm.nih.gov/pubmed/34474396 http://dx.doi.org/10.1016/j.redox.2021.102115 |
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