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Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage

Increased oxidative stress contributes to cataract formation during aging. Anterior epithelial cells are a frontline antioxidant defense system with powerful capacities to maintain redox homeostasis and lens transparency. In this study, we report a new molecular mechanism of connexin (Cx) hemichanne...

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Detalles Bibliográficos
Autores principales: Quan, Yumeng, Du, Yu, Wu, Changrui, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408634/
https://www.ncbi.nlm.nih.gov/pubmed/34474393
http://dx.doi.org/10.1016/j.redox.2021.102102