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Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage
Increased oxidative stress contributes to cataract formation during aging. Anterior epithelial cells are a frontline antioxidant defense system with powerful capacities to maintain redox homeostasis and lens transparency. In this study, we report a new molecular mechanism of connexin (Cx) hemichanne...
Autores principales: | Quan, Yumeng, Du, Yu, Wu, Changrui, Gu, Sumin, Jiang, Jean X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408634/ https://www.ncbi.nlm.nih.gov/pubmed/34474393 http://dx.doi.org/10.1016/j.redox.2021.102102 |
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