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Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

Four serine/threonine kinases are present in all mycobacteria: PknA, PknB, PknG and PknL. PknA and PknB are essential for growth and replication, PknG regulates metabolism, but little is known about PknL. Inactivation of pknL and adjacent regulator MSMEG_4242 in rough colony M. smegmatis mc(2)155 pr...

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Detalles Bibliográficos
Autores principales:	Báez-Ramírez, Estalina, Querales, Luis, Aranaga, Carlos Andres, López, Gustavo, Guerrero, Elba, Kremer, Laurent, Carrère-Kremer, Séverine, Viljoen, Albertus, Daffé, Mamadou, Laval, Françoise, Cole, Stewart T., Benjak, Andrej, Alzari, Pedro, André-Leroux, Gwenaëlle, Jacobs, William R., Vilcheze, Catherine, Takiff, Howard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408660/ https://www.ncbi.nlm.nih.gov/pubmed/34485766 http://dx.doi.org/10.1016/j.tcsw.2021.100060

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