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Sex Differences in Cognitive Abilities Among Children With the Autosomal Dominant Alzheimer Disease Presenilin 1 E280A Variant From a Colombian Cohort

IMPORTANCE: We previously reported that children with the autosomal dominant Alzheimer disease (ADAD) presenilin 1 (PSEN1) E280A variant had early life plasma biomarker findings consistent with amyloid β overproduction. However, the cognitive functioning of children with this variant has not been ch...

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Detalles Bibliográficos
Autores principales: Fox-Fuller, Joshua T., Artola, Arabiye, Chen, Kewei, Pulsifer, Margaret, Ramirez, Dora, Londono, Natalia, Aguirre-Acevedo, Daniel C., Vila-Castelar, Clara, Baena, Ana, Martinez, Jairo, Arboleda-Velasquez, Joseph F., Langbaum, Jessica B., Tariot, Pierre N., Reiman, Eric M., Lopera, Francisco, Quiroz, Yakeel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408665/
https://www.ncbi.nlm.nih.gov/pubmed/34463747
http://dx.doi.org/10.1001/jamanetworkopen.2021.21697