Cargando…
Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of thought, action, and emotion. PFC neurons generate top-down goals through recurrent excitatory connections on spines. Thi...
Autores principales: | Woo, Elizabeth, Sansing, Lauren H., Arnsten, Amy F. T., Datta, Dibyadeep |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408896/ https://www.ncbi.nlm.nih.gov/pubmed/34485797 http://dx.doi.org/10.1177/24705470211029254 |
Ejemplares similares
-
Glutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex
por: Woo, Elizabeth, et al.
Publicado: (2022) -
Loss of Prefrontal Cortical Higher Cognition with Uncontrollable Stress: Molecular Mechanisms, Changes with Age, and Relevance to Treatment
por: Datta, Dibyadeep, et al.
Publicado: (2019) -
The genie in the bottle-magnified calcium signaling in dorsolateral prefrontal cortex
por: Arnsten, Amy F. T., et al.
Publicado: (2020) -
Inhibition of glutamate-carboxypeptidase-II in dorsolateral prefrontal cortex: potential therapeutic target for neuroinflammatory cognitive disorders
por: Yang, Shengtao, et al.
Publicado: (2022) -
Glutamate Carboxypeptidase II in Aging Rat Prefrontal Cortex Impairs Working Memory Performance
por: Datta, Dibyadeep, et al.
Publicado: (2021)