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Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes

BACKGROUND: Epithelial ovarian cancer (OC) is a heterogenous disease consisting of five major histologically distinct subtypes: high-grade serous (HGSOC), low-grade serous (LGSOC), endometrioid (ENOC), clear cell (CCOC) and mucinous (MOC). Although HGSOC is the most prevalent subtype, representing 7...

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Detalles Bibliográficos
Autores principales: Barnes, Bethany M., Nelson, Louisa, Tighe, Anthony, Burghel, George J., Lin, I-Hsuan, Desai, Sudha, McGrail, Joanne C., Morgan, Robert D., Taylor, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408985/
https://www.ncbi.nlm.nih.gov/pubmed/34470661
http://dx.doi.org/10.1186/s13073-021-00952-5