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A three-gene signature based on MYC, BCL-2 and NFKBIA improves risk stratification in diffuse large B-cell lymphoma

Recent randomized trials focused on gene expression-based determination of the cell of origin in diffuse large B-cell lymphoma could not show significant improvements by adding novel agents to standard chemoimmunotherapy. The aim of this study was the identification of a gene signature able to refin...

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Detalles Bibliográficos
Autores principales: Derenzini, Enrico, Mazzara, Saveria, Melle, Federica, Motta, Giovanna, Fabbri, Marco, Bruna, Riccardo, Agostinelli, Claudio, Cesano, Alessandra, Corsini, Chiara Antonia, Chen, Ning, Righi, Simona, Sabattini, Elena, Chiappella, Annalisa, Calleri, Angelica, Fiori, Stefano, Tabanelli, Valentina, Cabras, Antonello, Pruneri, Giancarlo, Vitolo, Umberto, Gianni, Alessandro Massimo, Rambaldi, Alessandro, Corradini, Paolo, Zinzani, Pier Luigi, Tarella, Corrado, Pileri, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409021/
https://www.ncbi.nlm.nih.gov/pubmed/32817282
http://dx.doi.org/10.3324/haematol.2019.236455