Impaired nodal shrinkage and apoptosis define the independent adverse outcome of NOTCH1 mutated patients under ibrutinib therapy in chronic lymphocytic leukemia

The introduction of agents inhibiting the B-cell receptor-associated kinases such as ibrutinib has dramatically changed treatments algorithms of chronic lymphocytic leukemia (CLL) as well as the role of different adverse prognosticators. We evaluated the efficacy of ibrutinib as a single agent, in a...

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Detalles Bibliográficos
Autores principales: Del Poeta, Giovanni, Biagi, Annalisa, Laurenti, Luca, Chiarenza, Annalisa, Pozzo, Federico, Innocenti, Idanna, Postorino, Massimiliano, Rossi, Francesca Maria, Del Principe, Maria Ilaria, Bomben, Riccardo, de Fabritiis, Paolo, Bruno, Antonio, Cantonetti, Maria, Di Raimondo, Francesco, Zucchetto, Antonella, Gattei, Valter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409042/
https://www.ncbi.nlm.nih.gov/pubmed/32732360
http://dx.doi.org/10.3324/haematol.2020.251488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409042/
https://www.ncbi.nlm.nih.gov/pubmed/32732360
http://dx.doi.org/10.3324/haematol.2020.251488

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